GMCheck: Bayesian error checking for pedigreegenotypes and phenotypes
نویسنده
چکیده
GMCheck uses graphical modeling to find the posterior probabilities of data errors given genotypes or phenotypes in a specified pedigree structure.
منابع مشابه
A Probabilistic Model for COPD Diagnosis and Phenotyping Using Bayesian Networks
Introduction: This research was meant to provide a model for COPD diagnosis and to classify the cases into phenotypes; General COPD, Chronic bronchitis, Emphysema, and the Asthmatic COPD using a Bayesian Network (BN). Methods: The model was constructed through developing the Bayesian Network structure and instantiating the parameters for each of the variables. In order to validate the achiev...
متن کاملBayes, E-Bayes and Robust Bayes Premium Estimation and Prediction under the Squared Log Error Loss Function
In risk analysis based on Bayesian framework, premium calculation requires specification of a prior distribution for the risk parameter in the heterogeneous portfolio. When the prior knowledge is vague, the E-Bayesian and robust Bayesian analysis can be used to handle the uncertainty in specifying the prior distribution by considering a class of priors instead of a single prior. In th...
متن کاملImputation of parent-offspring trios and their effect on accuracy of genomic prediction using Bayesian method
The objective of this study was to evaluate the imputation accuracy of parent-offspring trios under different scenarios. By using simulated datasets, the performance Bayesian LASSO in genomic prediction was also examined. The genome consisted of 5 chromosomes and each chromosome was set as 1 Morgan length. The number of SNPs per chromosome was 10000. One hundred QTLs were randomly distributed a...
متن کاملComparison of Neural Network Models, Vector Auto Regression (VAR), Bayesian Vector-Autoregressive (BVAR), Generalized Auto Regressive Conditional Heteroskedasticity (GARCH) Process and Time Series in Forecasting Inflation in Iran
This paper has two aims. The first is forecasting inflation in Iran using Macroeconomic variables data in Iran (Inflation rate, liquidity, GDP, prices of imported goods and exchange rates) , and the second is comparing the performance of forecasting vector auto regression (VAR), Bayesian Vector-Autoregressive (BVAR), GARCH, time series and neural network models by which Iran's inflation is for...
متن کاملComparison of Estimates Using Record Statistics from Lomax Model: Bayesian and Non Bayesian Approaches
This paper address the problem of Bayesian estimation of the parameters, reliability and hazard function in the context of record statistics values from the two-parameter Lomax distribution. The ML and the Bayes estimates based on records are derived for the two unknown parameters and the survival time parameters, reliability and hazard functions. The Bayes estimates are obtained based on conju...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Bioinformatics
دوره 21 14 شماره
صفحات -
تاریخ انتشار 2005